Small Molecules and Biological Activities

نویسنده

  • Rana Morris
چکیده

The chemical and bioactivity resources at the National Center for Biotechnology Information (NCBI) are coordinated as part of the PubChem Project with data accessible as part of the PubChem Compound and Substance databases and PubChem BioAssay database, respectively. Currently the PubChem set of resources provides access to information about over 36 million chemical compounds and experimental studies with results for over 700 thousand biological activity assays.

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Investigation of the Molecules Obtained from Marijuana: Computational Study of Spectral, Structural and Docking

There are many chemical molecules whose names are Cannabigerol (CBG), cannabidol (CBD), cannabichromene (CBC), tetrahydrocannabivarin (THCV), cannabigerovarinic acid (CBGV) and cannabidiolic acid (CBDA) derived from Marijuana. Theoretical methods were used to compare the chemical and biological activities of the six major molecules. Molecules were compared with their chemical activities using m...

متن کامل

Improving biological activity prediction of protein kinase inhibitors using artificial neural network and partial least square methods

Introduction: Protein kinase causes many diseases, including cancer; therefore, inhibiting them plays an important role in the treatment of many diseases. Traditional discovery inhibitors of this enzyme is a time-consuming and costly process. Finding a reliable computer-aided drug discovery tools which can detect the inhibitors will reduce the cost. In this study, it is attempted to separate ki...

متن کامل

Improving biological activity prediction of protein kinase inhibitors using artificial neural network and partial least square methods

Introduction: Protein kinase causes many diseases, including cancer; therefore, inhibiting them plays an important role in the treatment of many diseases. Traditional discovery inhibitors of this enzyme is a time-consuming and costly process. Finding a reliable computer-aided drug discovery tools which can detect the inhibitors will reduce the cost. In this study, it is attempted to separate ki...

متن کامل

PubChem: Integrated Platform of Small Molecules and Biological Activities

PubChem is an open repository for experimental data identifying the biological activities of small molecules. PubChem contents include more than: 1,000 bioassays, 28 million bioassay test outcomes, 40 million substance contributed descriptions, and 19 million unique compound structures contributed from over 70 depositing organizations. PubChem provides a significant, publicly accessible platfor...

متن کامل

Analysis of Molecular Interactions Using the Thermophoresis Method and its Applications in Neuroscience and Biological Processes

Introduction: Molecular interactions play an important role in the phenomenon and biological processes. In fact, any cellular biological process ranged from genetic replication to the production of various proteins to the transmission of neurological, hormonal, membrane involves collections of molecular interactions that occur continuously. Interference in each of these processes at every stage...

متن کامل

Applications of Small Molecules in Muscle Tissue Engineering

Introduction: Skeletal muscles account for about 40% of the total body weight. Every year, hundreds of people lose at least part of their muscle tissue due to illness, war, and accidents. This can lead to disruption of activities such as breathing, movement, and social life. To this end, various therapeutic strategies such as medication therapy, cell therapy and tissue transplantation have been...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

عنوان ژورنال:

دوره   شماره 

صفحات  -

تاریخ انتشار 2017